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Beyond Health

Mariel Reid, APRN

Nevadomski Counseling

Jennifer Nevadomski, LPC

Drug / Gene Testing: PgX (Pharmacogenomic) Test

The PgX (Pharmacogenomic) Test is designed to personalize medication therapy based on an individual's unique genetic makeup. Pharmacogenomics examines how genetic variations influence an individual's response to drugs, enabling your healthcare provider to prescribe medications more effectively and minimize adverse drug reactions. 

 

This test analyzes specific genes involved in drug metabolism, drug transport, and drug targets to provide insights into how an individual's body processes medications. By identifying genetic variants that may impact drug processing, efficacy or toxicity, the PgX test empowers healthcare providers to make informed decisions about medication selection, dosage adjustments, and treatment plans tailored to each patient's genetic profile. 

 

Results from the PgX Pharmacogenetic Test by Trudiagnostic are presented inside a comprehensive result report, with the following sections:

  • Genetic Summary: a summary of the specific SNPs tested and the individual’s genetic results

  • Current Regimen Risk Detail (by severity): an assessment of the individual’s current medications and any risks apropos of the medication list supplied for the following risk vectors (Pharmacogenetic risks; Drug-to-drug interactions; Contraindications; AGS Beers criteria; Lifestyle factors; Anticholinergic burden; and FDA boxed warnings)

  • Medications Summary: a list of common medications by body system, graded as Likely Safe with Standard Precautions; Use Caution; or Change Recommended based on the individual’s pharmacogenetics

  • Medication Report Details (by therapeutic class): an in-depth report on the individual’s likely response to individual medications based on her or his pharmacogenetic report

 

PGx testing is a type of precision medicine, which uses information about a person's genes, lifestyle, and environment to find the best treatments and prevention strategies. 

PGx testing can also identify an increased risk for certain uncommon health conditions that were passed down from a person's parents. 

Preparation & Timing:​

Refrain from wearing lip balm and lipstick. Avoid eating, smoking, chewing gum, and drinking for 30 minutes before collection.

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Collection Instructions:

  • ​Complete online test registration before sample collection.  Click here to register your test.  

  • Wash hands and write date of birth on the vial.

  • Place the vial upright on a flat surface.

  • Open the vial.  DO NOT touch or discard the liquid.

  • Unwrap the swab.  DO NOT touch the cotton end that will go in your mouth.

  • Using a lot of pressure, rub swab against the inside of both cheeks for 60 seconds each, rotating the tip as you swab.  .

  • Pick up the vial.  Slowly insert and twist the swab into the vial, using a corkscrew motion.

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Move the swab rapidly up and down 10-15 times inside the tube, keeping the swab in the liquid the entire time.

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Using a corkscrew motion, slowly twist the swab to remove it from the vial. Seal vial tightly. Place the vial in the provided ziplock bag and packaging tube. Discard the swab.

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